Inhouse product
Introduction
Progut 40 Capsule is a medicine which reduces the amount of acid produced in your stomach. It is used to treat heartburn, acid reflux and problems in yo... View More
Uses of Progut 40 Capsule
Side effects of Progut 40 Capsule
How to use Progut 40 Capsule
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Progut 40 Capsule is to be... View More
How Progut 40 Capsule works
Progut 40 Capsule is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indiges... View More
What if you forget to take Progut 40 Capsule?
If you miss a dose of Progut 40 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back... View More
Indication
Heartburn, Acid Related Dyspepsia, Peptic ulcer disease, Zollinger-Ellison syndrome, Gastroesophageal reflux disease (GERD), Helicobacter pylori infecti... View More
Administration
Delayed-release cap: Should be taken on an empty stomach. Take on an empty stomach 1 hr before meals. Tab: May be taken with or without food.
Adult Dose
GERD Without Erosive Esophagitis 20 mg PO qDay for 4 weeks; consider an additional 4 weeks of treatment if symptoms do not resolve completely in the fi... View More
Child Dose
GERD Without Erosive Esophagitis Oral <1 year: Safety and efficacy not established 1-12 years: 10-20 mg PO qDay for up to 8 weeks >12 years: 20-40 m... View More
Renal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Esomeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted Benzimidazoles.
Mode of Action
Esomeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in the gastric parietal cell. It is the S-isomer of omeprazole.
Precaution
Paediatric; pregnancy, lactation. Malignancy and hepatic impairment. Increased risk of developing certain infections such as community-acquired pneumoni... View More
Side Effect
>10% Headache (2-11%) 1-10% Flatulence (10%),Indigestion (6%),Nausea (6%),Abdominal pain (1-6%),Diarrhea (2-4%),Xerostomia (3-4%),Dizziness (2-3%),... View More
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies in pregnant women; esomeprazole is the S-isomer of omeprazole; available epidemiologic data... View More
Interaction
Increased risk of digoxin-induced cardiotoxic effects. Increased risk of hypomagnesaemia w/ diuretics. May increase INR and prothrombin time w/ warfarin... View More
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