Inhouse product
Indication
Hypertension, Congestive heart failure, Oedema, Ascites
Adult Dose
Adult: Per tab contains furosemide 20 mg and spironolactone 50 mg. 1-4 tabs/day.
Contraindication
Hypersensitivity, anuria or severe oliguria, hypovolaemia, hyponatraemia, hypotension, urinary retention due to prostatic hypertrophy, Addison's disease... View More
Mode of Action
Furosemide inhibits reabsorption of Na+, Cl- and K+. Continuous use may also lead to secondary hyperaldosteronism. Spironolactone is a specific antagoni... View More
Precaution
Concomitant use with ACE inhibitors, monitor fluids and electrolytes including changes in serum K levels. Dilutional hyponatraemia or even a true low-sa... View More
Side Effect
Fluid and electrolyte imbalance, nausea, diarrhoea, blurred vision, headache, dizziness, hypotension, photosensitisation, hepatic dysfunction, hyperglyc... View More
Interaction
1. Frusemide: Aminoglycosides and ethacrynic acid (increased ototoxicity), tubocurazine, succinylcholine (effects enhanced). Sucralfate reduces effects ... View More
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